II. THE SIMULTANEOUS MEASUREMENT OF EXCHANGEABLE BODY SODIUM AND POTASSIUM UTILIZING ION EXCHANGE CHROMATOGRAPHY

Measurement of Total Body Exchangeable Potassium

Studies were undertaken to appraise the cellular potassium status of children with the nephrotic syndrome, utilizing two techniques: Measurement of total body exchangeable potassium (Ke) by isotope dilution and determination of the potassium content of red blood cells by direct chemical analysis. The Ke values obtained on the nephrotic children are compared to similar data obtained on "hospital...

I. The separation of sodium from potassium in human blood serum by ion exchange chromatography.

The experiments to be described were undertaken to devise a simple and rapid technique for the separation of sodium from potassium in human blood serum in order to facilitate the simultaneous measurement of exchangeable sodium and potassium in man by the isotope dilution technique. This technique requires the intravenous administration of a known amount of radioactive sodium (Na24) and radioact...

[Total exchangeable sodium, exchangeable potassium and total body water in some endocrine diseases].

概要 諸種 内分 泌疾患 々者についてtotal exchangeable sodium (Nae)お よびpotassium (Ke)を 測定 し,得 た成績 をtotal body water (TBW)か ら算出 したlean body massと の関連 において比較 した. 原発性 アル ドス テロ ン症ではNaeは 著増 し, Keは 減少 していた.一 方続発性 アル ドステ ロン症を伴な つた腎尿 細管 性 アシ ドージスでは, Naeお よびTBWの 増加は な くKeは 著減 していた. Cushing症 候 群 ではKeは 減少 していた. Addison病 では予想 されたNaeの 減少, Keの 増加 はみ られなかつた.褐 色 細胞腫 ではNae, Keお よびTBWは いずれ も正常 であつた.甲 状線機能亢 進症 ではNae増 加, Ke減 少 の傾 ...

Interrelations between total exchangeable sodium, potassium, body water, and serum sodium and potassium concentrations in hyponatremic and normonatremic heart disease.

Equations for the prediction of normal values for exchangeable sodium, exchangeable potassium, extracellular fluid volume, and total body water.

Despite the valuable research information on body electrolytes and water that is gained from isotope dilution studies, these investigations have not become routine clinical procedure. This is partly due to the fact that normal ranges for exchangeable sodium (NaE), exchangeable potassium (KE), extracellular fluid volume (E.C.F.V.), and total body water (T.B.W.) are wide owing to great individual...